New Directions
in New Therapies

The Device

The Device

SONS Device

The SONS System is a neurostimulation device which consists of two dependent products; a sphenoid sinus and olfactory nerve stimulation balloon catheter and an external electrical stimulation control module.

SONS CATHETER

The catheter is engineered with two balloons, each targeting the above anatomical regions. The catheter assembly delivers electrical stimulation into the olfactory mucosal nerves, spheno-palatine ganglion, trigeminal nerves, cranial nerves III, IV, V, VI, pituitary gland with hypothalamo-hypophysial tracts and into related neuro-anatomical structures including neural tracts originating from these structures.

SONS CONTROL MODULE

The control module regulates the amount of energy delivered to each balloon. This enables the ability to modulate the activity of neuronal circuits up or down, based upon a patients specific needs, in order to optimize the desired clinical outcome and to minimize unwanted side effects.

SONS STIMULATION STRATEGY

The Sphenoid and Olfactory Nerve Stimulation System (SONS*) is a new form of DBS that uses a catheter system to electrically stimulate up to 32 distinct nerve trunks (nerve fibers and their connected neurons) by transmitting energy to nerves and nerve tissue (neuropile) through the Sphenoid Sinus and the Olfactory Mucosa of the nasal cavity. These nerve centers provide transmission access to many centers of the brain, with thousands of nerve fibers projecting to the periphery of the medial forebrain bundle (MFB), which is a complex bundle of axons coming from the basal olfactory regions, the periamygladaloid region and the septal nuclei. This combination of stimulation and drug delivery access will jumpstart the neurons and correct the lack of key neurotransmitters in the brain.


 *SONS is currently designated as an investigational device and limited by U.S. Federal law to investigational use